CRISPR-Cas9 Gene Editing According to Maqasid al-Shariah: Ethical Concerns and Applications

Muhammad Syahmi Aqeel Shahridzuan

doi:10.55265/al-maqasid.v5i1.129

Authors

Muhammad Syahmi Aqeel Shahridzuan Faculty of Syariah and Law, Universiti Sains Islam Malaysia (USIM), Bandar Baru Nilai, Nilai 71800, Negeri Sembilan

DOI:

https://doi.org/10.55265/al-maqasid.v5i1.129

Keywords:

CRISPR-Cas9, Gene Editing, Islamic Bioethics, Maqasid al-Shari’ah, He Jiankui, Germline Editing, Ethical Concerns

Abstract

This paper explores the revolutionary CRISPR-Cas9 which is the gene-editing technology nowadays through the lens of Islamic bioethics, emphasizing its alignment with the Maqasid al-Shari’ah principles which have five that are preservation of life, wealth, faith, intellect, and lineage. While CRISPR-Cas9 offers ground-breaking potential in addressing genetic disorders and enhancing medical treatments, it also raises profound ethical and religious concerns. Key issues include its potential misuse for genetic enhancement, risks of unintended mutations, and challenges to the sanctity of human dignity and divine creation. The paper critiques He Jiankui’s controversial application of CRISPR-Cas9, highlighting violations of ethical and Islamic principles. It concludes with a call for stringent regulatory frameworks and adherence to ethical boundaries, ensuring CRISPR-Cas9 is employed solely for therapeutic purposes consistent with Islamic values.

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